Full text of peanut allergy breakthrough (enzyme) article

March 6, 2006 at 7:44 am (Allergy News!)

Peanut allergy breakthrough
Tuesday, February 28, 2006

Peanut butter. (Edmonton Journal, file).
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TORONTO — Toronto researchers say they’ve found a couple of clues in identifying who is at risk of dying from a peanut allergy.

As part of a joint team of international researchers, the Toronto allergy specialists studied the blood of people killed by peanut allergies and found that an enzyme may be at root of the problem.

Global National Online Extras
» Jennifer Tryon reports
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Dr. Peter Vadas says nine people who died of the allergy had significantly lower levels of a certain enzyme, which normally breaks down the chemical that causes bronchial spasms.

They also had high levels of certain antibodies that are activated during an allergic reaction.

This one-two biochemical punch wasn’t found in people who died of other causes, including allergic reactions to things other than peanuts.

Vadas, who heads the allergy and clinical immunology division of Toronto’s St. Michael’s Hospital, says to be at risk of dying from a peanut allergy, he believes people need to have those two factors to come together.


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